Key roles of autophagosome/endosome maturation mediated by Syntaxin17 in methamphetamine-induced neuronal damage in mice

• Main Authors: Xi Wang (Author), Miaoyang Hu (Author), Jingrong Chen (Author), Xinyu Lou (Author), Hongchao Zhang (Author), Muhan Li (Author), Jie Cheng (Author), Tengfei Ma (Author), Jianping Xiong (Author), Rong Gao (Author), Xufeng Chen (Author), Jun Wang (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Autophagic defects are involved in Methamphetamine (Meth)-induced neurotoxicity. Syntaxin 17 (Stx17), a member of the SNARE protein family, participating in several stages of autophagy, including autophagosome-late endosome/lysosome fusion. However, the role of Stx17 and potentia...