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Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders

Gene expression profiles are useful for assessing the efficacy and side effects of drugs. In this paper, we propose a new generative model that infers drug molecules that could induce a desired change in gene expression. Our model-the Bidirectional Adversarial Autoencoder-explicitly separates cellul...

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Bibliografski detalji
Glavni autori:	Rim Shayakhmetov (Autor), Maksim Kuznetsov (Autor), Alexander Zhebrak (Autor), Artur Kadurin (Autor), Sergey Nikolenko (Autor), Alexander Aliper (Autor), Daniil Polykovskiy (Autor)
Format:	Knjiga
Izdano:	Frontiers Media S.A., 2020-04-01T00:00:00Z.
Teme:	article
Online pristup:	Connect to this object online.
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