Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study

• Main Authors: Christina König (Author), Jens Martens-Lobenhoffer (Author), Patrick Czorlich (Author), Manfred Westphal (Author), Stefanie M. Bode-Böger (Author), Stefan Kluge (Author), Jörn Grensemann (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background For treatment of ventriculitis, vancomycin and meropenem are frequently used as empiric treatment but cerebrospinal fluid (CSF) penetration is highly variable and may result in subtherapeutic concentrations. Fosfomycin has been suggested for combination antibiotic therapy, but da...