RNAi targeting heparin cofactor II promotes hemostasis in hemophilia A

• Главные авторы: Wen-yi Lin (Автор), Ruiqi Zhu (Автор), Zhen Zhang (Автор), Xuan Lu (Автор), Huafang Wang (Автор), Wenjuan He (Автор), Yu Hu (Автор), Liang Tang (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2021-06-01T00:00:00Z.
• Предметы: article
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Hemophilia A is a hemorrhagic disease due to congenital deficiencies of coagulation factor VIII (FVIII). Studies show that hemophilia patients with anticoagulant deficiency present less severe hemorrhagic phenotypes. We aimed to find a new therapeutic option for hemophilia patients by RNA interferen...