RNAi targeting heparin cofactor II promotes hemostasis in hemophilia A

• Main Authors: Wen-yi Lin (Author), Ruiqi Zhu (Author), Zhen Zhang (Author), Xuan Lu (Author), Huafang Wang (Author), Wenjuan He (Author), Yu Hu (Author), Liang Tang (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hemophilia A is a hemorrhagic disease due to congenital deficiencies of coagulation factor VIII (FVIII). Studies show that hemophilia patients with anticoagulant deficiency present less severe hemorrhagic phenotypes. We aimed to find a new therapeutic option for hemophilia patients by RNA interferen...