Aplastic anemia with thrombopoietin gene mutation successfully treated with romiplostim monotherapy

• Main Authors: Niranjan Gurunath Hegde (Author), Deenadayalan Munirathnam (Author), Meena Sivasankaran (Author), Ravikumar Thangadorai (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Eltrombopag and romiplostim are thrombopoietin-receptor agonists (TPO-RA), which are approved globally for the treatment of immune thrombocytopenia. However, thrombopoietin (TPO) is not just a regulator of megakaryocyte expansion but is also a vital cytokine for hematopoietic stem cell m...