Chemical Variations on the p53 Reactivation Theme
Among the tumor suppressor genes, p53 is one of the most studied. It is widely regarded as the "guardian of the genome", playing a major role in carcinogenesis. In fact, direct inactivation of the TP53 gene occurs in more than 50% of malignancies, and in tumors that retain wild-type p53 st...
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Main Authors: | Carlos J. A. Ribeiro (Author), Cecília M. P. Rodrigues (Author), Rui Moreira (Author), Maria M. M. Santos (Author) |
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Format: | Book |
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MDPI AG,
2016-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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