Extract of Mallotus oppositifolius (Geiseler) Müll. Arg. increased prefrontal cortex dendritic spine density and serotonin and attenuated para-chlorophenylalanine-aggravated aggressive and depressive behaviors in mice

• Main Authors: Kennedy K.E. Kukuia (Author), Frimpong Appiah (Author), George J. Dugbartey (Author), Yaw F. Takyi (Author), Patrick Amoateng (Author), Seth K. Amponsah (Author), Ofosua Adi-Dako (Author), Awo E. Koomson (Author), Frederick Ayertey (Author), Kevin K. Adutwum-Ofosu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aim: Depression-related aggression is linked to serotonin (5-HT) and dendritic spine alterations. Although Mallotus oppositifolius extract (MOE) has potential for reducing this effect, its specific role remains uncertain. Herein, we evaluated this potential and associated alterations in t...