Toll-Like Receptors and Cytokines as Surrogate Biomarkers for Evaluating Vaginal Immune Response following Microbicide Administration

• Main Authors: Sadhana M. Gupta (Author), Clara C. Aranha (Author), Madhu C. Mohanty (Author), K. V. R. Reddy (Author)
• Format: Book
• Published: Hindawi Limited, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Topical microbicides are intended for frequent use by women in reproductive age. Hence, it is essential to evaluate their impact on mucosal immune function in the vagina. In the present study, we evaluated nisin, a naturally occurring antimicrobial peptide (AMP), for its efficacy as an intravaginal...