Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats

• Asıl Yazarlar: Wei-ren Lan (Yazar), Sai Pan (Yazar), Hai-yin Li (Yazar), Chao Sun (Yazar), Xian Chang (Yazar), Kang Lu (Yazar), Chang-qing Jiang (Yazar), Rui Zuo (Yazar), Yue Zhou (Yazar), Chang-qing Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Stem cell therapies for intervertebral disc degeneration have been demonstrated as a promising strategy. Previous studies have shown that human nucleus pulposus cell- (NPC-) derived exosomes can induce the differentiation of mesenchymal stem cells (MSCs) into NP-like cells in vitro. However, the mec...