Elevated Bile Acid 3β,5α,6β-Trihydroxycholanoyl Glycine in a Subset of Adult Ataxias Including Niemann-Pick Type C

Elevated Bile Acid 3β,5α,6β-Trihydroxycholanoyl Glycine in a Subset of Adult Ataxias Including Niemann-Pick Type C

Ataxia is a common neurological feature of Niemann-Pick disease type C (NPC). In this disease, unesterified cholesterol accumulates in lysosomes of the central nervous system and hepatic cells. Oxidation by reactive oxygen species produces oxysterols that can be metabolised to specific bile acids. T...

Full description

Saved in:
Bibliographic Details
Main Authors: Nazgol Motamed-Gorji (Author), Youssef Khalil (Author), Cristina Gonzalez-Robles (Author), Shamsher Khan (Author), Philippa Mills (Author), Hector Garcia-Moreno (Author), Heather Ging (Author), Ambreen Tariq (Author), Peter T. Clayton (Author), Paola Giunti (Author)
Format: Book
Published: MDPI AG, 2024-05-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items