Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties

• Main Authors: Brandon Dow Chan (Author), Wing-Yan Wong (Author), Magnolia Muk-Lan Lee (Author), Patrick Ying-Kit Yue (Author), Xiangrong Dai (Author), Karl Wah-Keung Tsim (Author), Wen-Luan Wendy Hsiao (Author), Mandy Li (Author), Xiao-Yi Li (Author), William Chi-Shing Tai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Pathological angiogenesis, the abnormal or excessive generation of blood vessels, plays an important role in many diseases including cancer, diabetic retinopathy, psoriasis, and arthritis. Additionally, increasing evidence supports the close linkage between angiogenesis and inflammatio...