GM-CSF production from human airway smooth muscle cells is potentiated by human serum

• Main Authors: Maria B. Sukkar (Author), J. Margaret Hughes (Author), Peter R. A. Johnson (Author), Carol L. Armour (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2000-01-01T00:00:00Z.
• Fag: article
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Recent evidence suggests that airway smooth muscle cells (ASMC) actively participate in the airway inflammatory process in asthma. Interleukin-1β (IL-1β) and tumour necrosis factor-α (TNF-α) induce ASMC to release inflammatory mediators in vitro. ASMC mediator release in vivo, however, may be influe...