Trigeminal, Visceral and Vestibular Inputs May Improve Cognitive Functions by Acting through the Locus Coeruleus and the Ascending Reticular Activating System: A New Hypothesis

• Main Authors: Vincenzo De Cicco (Author), Maria P. Tramonti Fantozzi (Author), Enrico Cataldo (Author), Massimo Barresi (Author), Luca Bruschini (Author), Ugo Faraguna (Author), Diego Manzoni (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It is known that sensory signals sustain the background discharge of the ascending reticular activating system (ARAS) which includes the noradrenergic locus coeruleus (LC) neurons and controls the level of attention and alertness. Moreover, LC neurons influence brain metabolic activity, gene express...