Anti-neuroinflammatory Activity of Elephantopus scaber L. via Activation of Nrf2/HO-1 Signaling and Inhibition of p38 MAPK Pathway in LPS-Induced Microglia BV-2 Cells

• Main Authors: Chim-Kei Chan (Author), Loh Teng-Hern Tan (Author), Shathiswaran N. Andy (Author), Muhamad Noor Alfarizal Kamarudin (Author), Bey-Hing Goh (Author), Habsah Abdul Kadir (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Elephantopus scaber L. (family: Asteraceae) has been traditionally utilized as a folkloric medicine and scientifically shown to exhibit anti-inflammatory activities in various in vivo inflammatory models. Given the lack of study on the effect of E. scaber in neuroinflammation, this study aimed to in...