Mechanistic Insights into Side Effects of Troglitazone and Rosiglitazone Using a Novel Inverse Molecular Docking Protocol

Thiazolidinediones form drugs that treat insulin resistance in type 2 diabetes mellitus. Troglitazone represents the first drug from this family, which was removed from use by the FDA due to its hepatotoxicity. As an alternative, rosiglitazone was developed, but it was under the careful watch of FDA...

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Hauptverfasser: Katarina Kores (Verfasst von), Janez Konc (Verfasst von), Urban Bren (Verfasst von)
Format: Buch
Veröffentlicht: MDPI AG, 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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