A new self-emulsifying formulation of mefenamic acid with enhanced drug dissolution

• Main Authors: Pornsak Sriamornsak (Author), Sontaya Limmatvapirat (Author), Suchada Piriyaprasarth (Author), Punyanutch Mansukmanee (Author), Zongkang Huang (Author)
• Format: Book
• Published: Elsevier, 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To enhance the dissolution of poorly soluble mefenamic acid, self-emulsifying formulation (SEF), composing of oil, surfactant and co-surfactant, was formulated. Among the oils and surfactants studied, Imwitor® 742, Tween® 60, Cremophore® EL and Transcutol® HP were selected as they showed maximal sol...