A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval invasion through binding to RACK1 and activating MAPK/ERK1/2 pathway.

• Үндсэн зохиолчид: Yan Yan Song (Зохиогч), Xin Zhuo Zhang (Зохиогч), Bo Ning Wang (Зохиогч), Yong Kang Cheng (Зохиогч), Xin Guo (Зохиогч), Xi Zhang (Зохиогч), Shao Rong Long (Зохиогч), Ruo Dan Liu (Зохиогч), Zhong Quan Wang (Зохиогч), Jing Cui (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

<h4>Background</h4>Gut epithelium is the first natural barrier against Trichinella spiralis larval invasion, but the mechanism by which larval penetration of gut epithelium is not completely elucidated. Previous studies showed that proteases secreted by T. spiralis intestinal infective l...