Interleukin-1β and interleukin-6 gene polymorphisms in Egyptian sickle cell disease patients

• Main Authors: Yasmine Elammary (Author), Nadia Sewelam (Author), Hanan Al-Wakeel (Author), Mona El-Ghamrawy (Author), Shahira Zayed (Author)
• Formato: Livro
• Publicado em: SpringerOpen, 2020-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Sickle cell disease (SCD) is a disorder characterized by a heterogeneous clinical outcome. Interleukin-1β (IL-1β) and interleukin-6 (IL-6) are important mediators of inflammatory response. Genetic modifiers that alter cytokine levels may contribute to the clinical variability of...