Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio}acetamide as a promising anticonvulsant

• Main Authors: Hanna I. Severina (Author), Olga O. Skupa (Author), Natalya I. Voloshchuk (Author), Narzullo Saidov (Author), Vera A. Bunyatyan (Author), Sergiy M. Kovalenko (Author), Victoriya A. Georgiyants (Author)
• Format: Book
• Published: Belgorod National Research University, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The search for new anticonvulsants for epilepsy treatment with higher efficacy and better tolerability remains important. The aim of the present research was an in silico and in vivo pharmacological study of N-(3,4-dimethoxyphenyl)-2-((2-methyl-6-(pyridin-2-yl)pyrimidin-4-yl)thio)aceta...