Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio}acetamide as a promising anticonvulsant

• Hauptverfasser: Hanna I. Severina (Verfasst von), Olga O. Skupa (Verfasst von), Natalya I. Voloshchuk (Verfasst von), Narzullo Saidov (Verfasst von), Vera A. Bunyatyan (Verfasst von), Sergiy M. Kovalenko (Verfasst von), Victoriya A. Georgiyants (Verfasst von)
• Format: Buch
• Veröffentlicht: Belgorod National Research University, 2020-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Introduction: The search for new anticonvulsants for epilepsy treatment with higher efficacy and better tolerability remains important. The aim of the present research was an in silico and in vivo pharmacological study of N-(3,4-dimethoxyphenyl)-2-((2-methyl-6-(pyridin-2-yl)pyrimidin-4-yl)thio)aceta...