A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein

• Main Authors: Ziqiao Yuan (Author), Zihang Yuan (Author), Muhammad Hasnat (Author), Haoran Zhang (Author), Peishi Liang (Author), Lixin Sun (Author), Zhenzhou Jiang (Author), Luyong Zhang (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously, we proposed a new perspective of triptolide (TP)-associated hepatotoxicity: liver hypersensitivity upon lipopolysaccharide (LPS) stimulation. However, the mechanisms for TP/LPS-induced hepatotoxicity remained elusive. The present study aimed to clarify the role of LPS in TP/LPS-induced h...