Synthesis and antidiabetic activity of β-acetamido ketones

This paper reports the use of trifluoroacetic acid as a catalyst in the Dakin-West reaction for the synthesis of β-acetamido ketones. The method has several advantages such as requiring only mild conditions and a low concentration of catalyst. Screening of 19 β-acetamido ketones for antidiabetic act...

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Main Authors: Xing-hua Zhang (Author), Ju-fang Yan (Author), Li Fan (Author), Gong-bao Wang (Author), Da-cheng Yang (Author)
Format: Book
Published: Elsevier, 2011-08-01T00:00:00Z.
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