What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells?

• Main Authors: R. N. Bárcia (Author), J. M. Santos (Author), M. Filipe (Author), M. Teixeira (Author), J. P. Martins (Author), J. Almeida (Author), A. Água-Doce (Author), S. C. P. Almeida (Author), A. Varela (Author), S. Pohl (Author), K. E. J. Dittmar (Author), S. Calado (Author), S. I. Simões (Author), M. M. Gaspar (Author), M. E. M. Cruz (Author), W. Lindenmaier (Author), L. Graça (Author), H. Cruz (Author), P. E. Cruz (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MSCs derived from the umbilical cord tissue, termed UCX, were investigated for their immunomodulatory properties and compared to bone marrow-derived MSCs (BM-MSCs), the gold-standard in immunotherapy. Immunogenicity and immunosuppression were assessed by mixed lymphocyte reactions, suppression of ly...