Radiosynthesis of Stable ¹⁹⁸Au-Nanoparticles by Neutron Activation of α_vβ₃-Specific AuNPs for Therapy of Tumor Angiogenesis

• Váldodahkkit: Güllü Davarci (Dahkki), Carmen Wängler (Dahkki), Klaus Eberhardt (Dahkki), Christopher Geppert (Dahkki), Ralf Schirrmacher (Dahkki), Robert Freudenberg (Dahkki), Marc Pretze (Dahkki), Björn Wängler (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs) activated by neutron irradiation as a therapeutic option for the treatment of cancer with high tumor angiogenesis. The AuNPs were designed with different mono- or dithiol-ligands and decorated with different am...