Indolium 1 Exerts Activity against Vemurafenib-Resistant Melanoma In Vivo

• Main Authors: Rakan Radi (Author), Christina Huang (Author), Justin Elsey (Author), Yoon H. Jung (Author), Victor G. Corces (Author), Jack L. Arbiser (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of targeted therapies (BRAF/MEK inhibitors) and immunotherapy have had a major impact on the treatment of melanoma. However, the majority of patients with advanced melanomas succumb to their disease. The mechanisms of resistance to both targeted therapies and immunotherapies are nume...