HIF-1α pathway: role, regulation and intervention for cancer therapy

• Main Authors: Georgina N. Masoud (Author), Wei Li (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2015-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Hypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong correlation between elevated levels of HIF-1 and tumor metastasis, angiogenesis, poor patient prognosis as well as tumor resistance therapy. It...