Differentiation in pyroptosis induction by Burkholderia pseudomallei and Burkholderia thailandensis in primary human monocytes, a possible cause of sepsis in acute melioidosis patients.

• Hoofdauteurs: Suphasuta Khongpraphan (Auteur), Peeraya Ekchariyawat (Auteur), Sucharat Sanongkiet (Auteur), Chularat Luangjindarat (Auteur), Stitaya Sirisinha (Auteur), Marisa Ponpuak (Auteur), Panuwat Midoeng (Auteur), Matsayapan Pudla (Auteur), Pongsak Utaisincharoen (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2024-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Melioidosis caused by Burkholderia pseudomallei is an infectious disease with a high mortality rate. In acute melioidosis, sepsis is a major cause of death among patients. Once the bacterium enters the bloodstream, immune system dysregulation ensues, leading to cytokine storms. In contrast to B. pse...