A Reference Profile of N-Glycosylation for Human Kidney and the Identification of Cell-Cell Interactions between Parietal Epithelial Cells and Capillary Endothelial Cells by Single-Cell Glycosylation-Sequencing

• Main Authors: Mengyun Xiao (Author), Qiang Yan (Author), Shaodong Luan (Author), Liusheng Lai (Author), Zigan Xu (Author), Yaoshuang Zou (Author), Zhipeng Zeng (Author), Haitao Li (Author), Jing Qiu (Author), Donge Tang (Author), Lianghong Yin (Author), Yong Dai (Author)
• Format: Book
• Published: Karger Publishers, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: N-glycosylation is one of the most common posttranslational modifications in humans, and these alterations are associated with kidney diseases. Methods: A novel technological approach, single-cell N-acetyllactosamine sequencing (scLacNAc-seq), was applied to simultaneously detect N-glyco...