Safety and efficacy of p38 mitogen-activated protein kinase inhibitors (MAPKIs) in COPD

• Main Authors: Haichuan Yu (Author), Xiaojie Su (Author), Ting Lei (Author), Lu Zhang (Author), Zhouzhou Feng (Author), Chuchu Zhang (Author), Meng Zhang (Author), Yalei Wang (Author), Xinlong Chen (Author), Jian Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Chronic inflammation is the core mechanism of the development of chronic obstructive pulmonary disease (COPD). Corticosteroid resistance in COPD limits its anti-inflammatory potency. p38 MAPKIs were suggested as an alternative to corticosteroids despite the fact that there is currently...