Danshensu methyl ester enhances autophagy to attenuate pulmonary fibrosis by targeting lncIAPF-HuR complex

• Main Authors: Qi Zhu (Author), Jing Wang (Author), Yunxia Ji (Author), Jianlin Luan (Author), Dayong Yue (Author), Weili Liu (Author), Hongbo Li (Author), Jinjin Zhang (Author), Guiwu Qu (Author), Changjun Lv (Author), Xiaodong Song (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Pulmonary fibrosis is an irreversible fibrotic process that has a high mortality rate and limited treatment options; thus, developing a novel therapeutic drug is critical. In this study, we synthesized danshensu methyl ester (DME) and explored its anti-pulmonary fibrotic ability on TGF-β1-stimulated...