Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals

• 主要な著者: Esam M. Aboubakr (著者), Ahmed R. N. Ibrahim (著者), Fares E. M. Ali (著者), Ahmed A. E. Mourad (著者), Adel M. Ahmad (著者), Amal Hofni (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Methotrexate (MTX) is one of the most widely used cytotoxic chemotherapeutic agents, and it is used in the treatment of different autoimmune disorders. However, the clinical applications of MTX are limited by its hepatic toxicity. Hence, the present study was conducted to evaluate the efficacy of fa...