Patch clamp studies on TRPV4-dependent hemichannel activation in lens epithelium

• मुख्य लेखकों: Jose F. Ek-Vitorin (लेखक), Mohammad Shahidullah (लेखक), Joaquin E. Lopez Rosales (लेखक), Nicholas A. Delamere (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

ATP release from the lens via hemichannels has been explained as a response to TRPV4 activation when the lens is subjected to osmotic swelling. To explore the apparent linkage between TRPV4 activation and connexin hemichannel opening we performed patch-clamp recordings on cultured mouse lens epithel...