New roles for prokineticin 2 in feeding behavior, insulin resistance and type 2 diabetes: Studies in mice and humans

• Main Authors: Marie Mortreux (Author), Ewout Foppen (Author), Raphaël G. Denis (Author), Mireia Montaner (Author), Nadim Kassis (Author), Jessica Denom (Author), Mylène Vincent (Author), Frédéric Fumeron (Author), Margaux Kujawski-Lafourcade (Author), Fabrizio Andréelli (Author), Beverley Balkau (Author), Michel Marre (Author), Ronan Roussel (Author), Christophe Magnan (Author), Hirac Gurden (Author), Stéphanie Migrenne-Li (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Prokineticin 2 (PROK2) is a hypothalamic neuropeptide that plays a critical role in the rhythmicity of physiological functions and inhibits food intake. PROK2 is also expressed in the main olfactory bulb (MOB) as an essential factor for neuro-and morphogenesis. Since the MOB was shown to...