The effect of high dose digoxin on cytokines in healthy dogs

• Main Authors: Haluk Dülger (Author), Mehmet Ramazan Şekeroğlu (Author), Beyhan Eryonucu (Author), Tevfik Noyan (Author), Süleyman Alici (Author)
• Format: Book
• Published: Hindawi Limited, 2002-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs fo...