Gallic Acid-Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation

• Główni autorzy: André Miranda (Autor), Roi Lopez-Blanco (Autor), Jéssica Lopes-Nunes (Autor), Ana M. Melo (Autor), Maria Paula Cabral Campello (Autor), António Paulo (Autor), Maria Cristina Oliveira (Autor), Jean-Louis Mergny (Autor), Paula A. Oliveira (Autor), Eduardo Fernandez-Megia (Autor), Carla Cruz (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-11-01T00:00:00Z.
• Hasła przedmiotowe: article
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Herein, we describe the synthesis of an aptadendrimer by covalent bioconjugation of a gallic acid-triethylene glycol (GATG) dendrimer with the G-quadruplex (G4) AT11 aptamer (a modified version of AS1411) at the surface. We evaluated the loading and interaction of an acridine orange ligand, termed C...