Gallic Acid-Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation

Gallic Acid-Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation

Herein, we describe the synthesis of an aptadendrimer by covalent bioconjugation of a gallic acid-triethylene glycol (GATG) dendrimer with the G-quadruplex (G4) AT11 aptamer (a modified version of AS1411) at the surface. We evaluated the loading and interaction of an acridine orange ligand, termed C...

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Main Authors: André Miranda (Author), Roi Lopez-Blanco (Author), Jéssica Lopes-Nunes (Author), Ana M. Melo (Author), Maria Paula Cabral Campello (Author), António Paulo (Author), Maria Cristina Oliveira (Author), Jean-Louis Mergny (Author), Paula A. Oliveira (Author), Eduardo Fernandez-Megia (Author), Carla Cruz (Author)
Format: Book
Published: MDPI AG, 2022-11-01T00:00:00Z.
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