Six-minute walk test as clinical end point in cardiomyopathy clinical trials, including ATTR-CM: a systematic literature review

• Main Authors: Jose Nativi-Nicolau (Author), Ali Yilmaz (Author), Noel Dasgupta (Author), Richard Macey (Author), James Cochrane (Author), Judith Peatman (Author), Catherine Summers (Author), Jennifer Luth (Author), Ronald Zolty (Author)
• Format: Book
• Published: Becaris Publishing Limited, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: The six-minute walk test (6MWT) is a common measure of functional capacity in patients with heart failure (HF). Primary clinical study end points in cardiomyopathy (CM) trials, including transthyretin-mediated amyloidosis with CM (ATTR-CM), are often limited to hospitalization and mortality. Ob...