Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities

Fluoroquinolones are synthetic antibacterial agents that stabilize the ternary complex of prokaryotic topoisomerase II enzymes (gyrase and Topo IV), leading to extensive DNA fragmentation and bacteria death. Despite the similar structural folds within the critical regions of prokaryotic and eukaryot...

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Bibliographic Details
Main Authors: Temilolu Idowu (Author), Frank Schweizer (Author)
Format: Book
Published: MDPI AG, 2017-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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