Prediction of Survival Benefit of Filgrastim in Adult and Pediatric Patients With Acute Radiation Syndrome

• Main Authors: John Harrold (Author), Per Olsson Gisleskog (Author), Juan Jose Perez‐Ruixo (Author), Isabelle Delor (Author), Andrew Chow (Author), Philippe Jacqmin (Author), Murad Melhem (Author)
• Format: Book
• Published: Wiley, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute exposure to high doses of radiation leads to severe myelosuppression, but few treatments are currently available to treat hematopoietic syndrome of acute radiation syndrome. Granulocyte colony stimulating factors (e.g., filgrastim) stimulate proliferation of neutrophil precursors and enhance m...