Model Re-Estimation: An Alternative for Poor Predictive Performance during External Evaluations? Example of Gentamicin in Critically Ill Patients

• Main Authors: Alexandre Duong (Author), Chantale Simard (Author), David Williamson (Author), Amélie Marsot (Author)
• 格式: 图书
• 出版: MDPI AG, 2022-07-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: An external evaluation is crucial before clinical applications; however, only a few gentamicin population pharmacokinetic (PopPK) models for critically ill patients included it in the model development. In this study, we aimed to evaluate gentamicin PopPK models developed for critically...