The A2B Adenosine Receptor Modulates the Epithelial- Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells

• Main Authors: Chiara Giacomelli (Author), Simona Daniele (Author), Chiara Romei (Author), Laura Tavanti (Author), Tommaso Neri (Author), Ilaria Piano (Author), Alessandro Celi (Author), Claudia Martini (Author), Maria L. Trincavelli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The epithelial-mesenchymal transition (EMT) is a complex process in which cell phenotype switches from the epithelial to mesenchymal one. The deregulations of this process have been related with the occurrence of different diseases such as lung cancer and fibrosis. In the last decade, several effort...