Pharmacokinetic enhancement of oncolytic virus M1 by inhibiting JAK‒STAT pathway

• Main Authors: Jingyi Tan (Author), Jiayu Zhang (Author), Cheng Hu (Author), Gongwei Wang (Author), Qianyao Ren (Author), Chaoqun Wang (Author), Jia Dan (Author), Zexin Zeng (Author), Jun Hu (Author), Wenbo Zhu (Author), Jiankai Liang (Author), Jing Cai (Author), Ying Liu (Author), Guangmei Yan (Author), Yuan Lin (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oncolytic viruses (OVs), a group of replication-competent viruses that can selectively infect and kill cancer cells while leaving healthy cells intact, are emerging as promising living anticancer agents. Unlike traditional drugs composed of non-replicating compounds or biomolecules, the replicative...