Influence of Carbamazepine Dihydrate on the Preparation of Amorphous Solid Dispersions by Hot Melt Extrusion

• मुख्य लेखकों: Xiangyu Ma (लेखक), Felix Müller (लेखक), Siyuan Huang (लेखक), Michael Lowinger (लेखक), Xu Liu (लेखक), Rebecca Schooler (लेखक), Robert O. Williams (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Amorphous solid dispersions (ASDs) are commonly used in the pharmaceutical industry to improve the dissolution and bioavailability of poorly water-soluble drugs. Hot melt extrusion (HME) has been employed to prepare ASD based products. However, due to the narrow processing window of HME, ASDs are no...