Stromal Derived Factor-1/CXCR4 Axis Involved in Bone Marrow Mesenchymal Stem Cells Recruitment to Injured Liver

• Main Authors: Kuai Xiao Ling (Author), Li Peng (Author), Zhang Jian Feng (Author), Cao Wei (Author), Yuan Wei Yan (Author), Shao Nan (Author), Guan Cheng Qi (Author), Wang Zhi Wei (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The molecular mechanism of bone marrow mesenchymal stromal stem cells (BMSCs) mobilization and migration to the liver was poorly understood. Stromal cell-derived factor-1 (SDF-1) participates in BMSCs homing and migration into injury organs. We try to investigate the role of SDF-1 signaling in BMSCs...