Immune checkpoint CD161/LLT1‐associated immunological landscape and diagnostic value in oral squamous cell carcinoma

• Main Authors: Xinyang Hu (Author), Yuexin Dong (Author), Shixin Xie (Author), Yuxian Song (Author), Chenhang Yu (Author), Yijia He (Author), Zhiyong Wang (Author), Qingang Hu (Author), Yanhong Ni (Author), Liang Ding (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract An active host adaptive response is characterized by the existence of programmed cell death protein 1 (PD‐1)+/IFN‐γ+ cytotoxic T cells and IFN‐γ‐induced PD‐L1+ tumor cells (TCs), which predicts high response rate to anti‐PD‐1/L1 therapy. Recently, CD161 and its ligand LLT1 (CLEC2D) have bee...