Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

• 主要な著者: K. Esparza (著者), S. D. Oliveira (著者), M. Castellon (著者), R. D. Minshall (著者), H. Onyuksel (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2023-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...