Impact of "time zero" of Follow-Up Settings in a Comparative Effectiveness Study Using Real-World Data with a Non-user Comparator: Comparison of Six Different Settings

• Main Authors: Ryozo Wakabayashi (Author), Takahiro Hirano (Author), Thomas Laurent (Author), Yoshiki Kuwatsuru (Author), Ryohei Kuwatsuru (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Time-related bias can lead to misleading conclusions. Properly setting the "time zero" of follow-up is crucial for avoiding these biases. However, the time-zero setting is challenging when comparing users and non-users of a study drug because the latter do not have a ti...