Acacetin inhibits inflammation by blocking MAPK/NF-κB pathways and NLRP3 inflammasome activation

• Główni autorzy: Juan Bu (Autor), Yeledan Mahan (Autor), Shengnan Zhang (Autor), Xuanxia Wu (Autor), Xiaoling Zhang (Autor), Ling Zhou (Autor), Yanmin Zhang (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objective: Our preliminary research indicates that acacetin modulates the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing 3 (NLRP3) inflammasome, providing protection against Alzheimer's Disease (AD) and cerebral ischemic reperfusion injury. The mechanisms...