Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy.

• Main Authors: Tulika Singh (Author), Cesar A Lopez (Author), Camila Giuberti (Author), Maria L Dennis (Author), Hannah L Itell (Author), Holly J Heimsath (Author), Helen S Webster (Author), Hunter K Roark (Author), Paulo R Merçon de Vargas (Author), Allison Hall (Author), Ralph G Corey (Author), Geeta K Swamy (Author), Reynaldo Dietze (Author), Helen M Lazear (Author), Sallie R Permar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zika virus (ZIKV) is a newly-identified infectious cause of congenital disease. Transplacental transfer of maternal IgG to the fetus plays an important role in preventing many neonatal infections. However, antibody transfer may also have negative consequences, such as mediating enhancement of flaviv...