Scutellarin Increases Cisplatin-Induced Apoptosis and Autophagy to Overcome Cisplatin Resistance in Non-small Cell Lung Cancer via ERK/p53 and c-met/AKT Signaling Pathways

• Main Authors: Chao-Yue Sun (Author), Ying Zhu (Author), Xiao-Feng Li (Author), Xie-Qi Wang (Author), Li-Peng Tang (Author), Zu-Qing Su (Author), Cai-Yun Li (Author), Guang-Juan Zheng (Author), Bing Feng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin, as the first-line anti-tumor agent, is widely used for treatment of a variety of malignancies including non-small cell lung cancer (NSCLC). However, the acquired resistance has been a major obstacle for the clinical application. Scutellarin is a active flavone extracted from Erigeron brev...