Celecoxib/Cyclodextrin Eye Drop Microsuspensions: Evaluation of In Vitro Cytotoxicity and Anti-VEGF Efficacy for Retinal Diseases

• Main Authors: Phatsawee Jansook (Author), Hay Man Saung Hnin Soe (Author), Rathapon Asasutjarit (Author), Theingi Tun (Author), Hay Marn Hnin (Author), Phyo Darli Maw (Author), Tanapong Watchararot (Author), Thorsteinn Loftsson (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Celecoxib (CCB), a cyclooxygenase-2 inhibitor, is capable of reducing oxidative stress and vascular endothelial growth factor (VEGF) expression in retinal cells and has been shown to be effective in the treatment of diabetic retinopathy and age-related macular degeneration. However, the ocular bioav...