Hydropersulfides (RSSH) Outperform Post-Conditioning and Other Reactive Sulfur Species in Limiting Ischemia-Reperfusion Injury in the Isolated Mouse Heart

• Main Authors: Blaze M. Pharoah (Author), Vinayak S. Khodade (Author), Alexander Eremiev (Author), Eric Bao (Author), Ting Liu (Author), Brian O'Rourke (Author), Nazareno Paolocci (Author), John P. Toscano (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydrogen sulfide (H₂S) exhibits protective effects in cardiovascular disease such as myocardial ischemia/reperfusion (I/R) injury, cardiac hypertrophy, and atherosclerosis. Despite these findings, its mechanism of action remains elusive. Recent studies suggest that H<sub>...